Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11051)
Related Products (11051)
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Lapatinib-13C215N
0 ImagesCat. No.: HY-W777297CAS No.: 1246819-08-8Lapatinib-13C2,15N Ditosylate is the 13C- and 15N-labeled Lapatinib ditosylate (HY-50898A). Lapatinib ditosylate (GW572016 ditosylate) is a potent inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.
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Dansyl acid-d6
0 ImagesCat. No.: HY-W268193SCAS No.: 1329836-02-3Dansyl acid-d6 is the deuterium labeled Propan-2-amine hydrochloride.
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Duostatin 5-13C,d3
0 ImagesCat. No.: HY-145149SDuostatin 5-13C,d3 is the 13C-labeled Duostatin 5 (HY-145149). Duostatin 5 is a ADC Cytotoxin designed based on MMAF (HY-15579) and can be used to synthesize ADCs. The preparation of Duostatin 5 has the advantages of fewer synthetic steps, simple operation, less difficulty in quality control, and more stable chemical synthesis process. Duostatin 5 can be linked to the antibody targeting 5T4 (ZV05) by cross-linking with interchain cysteines through a disubstituted C-Lock linker. Duostatin 5 is a click chemistry reagent. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-driven alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups[1][2].
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Nilvadipine-d4
0 ImagesCat. No.: HY-14284SCAS No.: 2928067-26-7Nilvadipine-d4 is deuterium labeled Nilvadipine. Nilvadipine is a potent calcium channel antagonist, and the IC50 value is around 0.1 nM.
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2'-Deoxyuridine-2′-13C
0 ImagesCat. No.: HY-D0186S1CAS No.: 478510-87-12'-Deoxyuridine-2′-13C is the 13C labeled 2'-Deoxyuridine. 2'-Deoxyuridine could increase chromosome breakage and results in a decreased thymidylate synthetase activity. A known use of 2'-Deoxyuridine is as a precursor in the synthesis of Edoxud[1]-
Didecyl phthalate-d4
0 ImagesCat. No.: HY-W010875SCAS No.: 1276197-18-2Didecyl phthalate-d4 is the deuterium labeled Didecyl phthalate.
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Empagliflozin-d8
0 ImagesCat. No.: HY-166652SCAS No.: 2714418-84-3Empagliflozin-d8 is the deuterium labeled Empagliflozin. Empagliflozin (BI 107730 is a selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with an IC50 of 3.1 nM for human SGLT-2.
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Erucic acid-d18-1
0 ImagesCat. No.: HY-N7109S3Erucic acid-d18-1 is the deuterium labeled Erucic acid (HY-N7109). Erucic acid, a monounsaturated fatty acid (MUFA), is isolated from the seed of Raphanus sativus L. Erucic acid can readily cross the blood-brain barrier (BBB), it has been reported to normalize the accumulation of very long-chain fatty acids in the brain. Erucic acid can improve cognitive impairment and be effective against dementia.
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6PPD-Quinone methyl ester-d5
0 ImagesCat. No.: HY-W754406Synonyms: Methyl carboxylate 6ppd-quinone-d56PPD-Quinone methyl ester-d5 (Methyl carboxylate 6ppd-quinone-d5) is the deuterium labeled 6PPD-Quinone methyl ester.
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Sulfaguanidine-d4
0 ImagesCat. No.: HY-B1267SPurity: 98.0%Sulfaguanidine-d4 is the deuterium labeled Sulfaguanidine. Sulfaguanidine, belongs to the class of sulfonamide agent, is an orally active antibiotic. Sulfaguanidine can be used for the research of enteric infections such as bacillary dysentery.
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11-([1,1':3',1''-Terphenyl]-3-yl)-11,12-dihydroindolo[2,3-a]carbazole-d22
![11-([1,1':3',1''-Terphenyl]-3-yl)-11,12-dihydroindolo[2,3-a]carbazole-d22](https://file.medchemexpress.com/product_pic/hy-184762s.gif "Click to View 11-([1,1':3',1''-Terphenyl]-3-yl)-11,12-dihydroindolo[2,3-a]carbazole-d22 Product Detail")
0 ImagesCat. No.: HY-184762S11-([1,1':3',1''-Terphenyl]-3-yl)-11,12-dihydroindolo[2,3-a]carbazole-d22 is the deuterium labeled 11-([1,1':3',1''-Terphenyl]-3-yl)-11,12-dihydroindolo[2,3-a]carbazole.
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1,2-Dihexanoyl-sn-glycero-3-phosphocholine-d31
0 ImagesCat. No.: HY-W127457S31,2-Dihexanoyl-sn-glycero-3-phosphocholine-d31 is the deuterium labeled 1,2-Dihexanoyl-sn-glycero-3-phosphocholine. 1,2-Dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine. It can play a role as a surfactant and is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.
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Acipimox-d4
0 ImagesCat. No.: HY-B0283SCAS No.: 1246816-28-3Synonyms: K-9321-d4Acipimox-d4 is the deuterium labeled Acipimox. Acipimox (K-9321), a nicotinic acid analogue, is an antilipolytic compound. Acipimox acutely inhibits lipolysis and suppresses systemic levels of free fatty acids (FFAs) and improves insulin sensitivity.
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Famotidine-13C3
0 ImagesCat. No.: HY-W777002CAS No.: 1185241-48-8Synonyms: MK-208-13C3Famotidine-13C3 (MK-208-13C3) is the 13C3-labeled Famotidine (HY-B0377). Famotidine (MK-208) is an orally active and highly selective histamine H2 receptor antagonist. It inhibits gastric acid secretion by blocking the Gs signaling pathway, and regulates intracellular cAMP and ERK pathways. Famotidine inhibits TLR3-mediated inflammatory pathways, and reduces the expression of various inflammatory mediators and interferon-related genes. Famotidine scavenges DPPH and nitric oxide free radicals, alleviates oxidative stress damage in gastric tissue, inhibits proMMP-9, improves vascular endothelial permeability, and restores the normal physiological functions of neutrophils and eosinophils. Famotidine crosses intestinal epithelial cells via facilitated diffusion and passive diffusion, blocks paracellular cation transport, and increases intestinal transepithelial electrical resistance. Famotidine reduces serum levels of transaminases and alkaline phosphatase, exerts analgesic effects and gastric protective effects simultaneously. Famotidine can be used in studies related to COVID-19, liver injury and acute gastric ulcer.
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L-Thyroxine-13C9,15N
0 ImagesCat. No.: HY-18341S3CAS No.: 1431868-11-9
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Agmatine-d8 sulfate
0 ImagesCat. No.: HY-101238SCAS No.: 909556-32-7Agmatine-d8 sulfate is a deuterium labeled Agmatine sulfate (HY-101238). Agmatine sulfate exerts modulatory action at multiple molecular targets, such as neurotransmitter systems, ion channels and nitric oxide synthesis. It is an endogenous agonist at imidazoline receptor and a NO synthase inhibitor.
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N-Acetyl-L-glutamic acid-d4
0 ImagesCat. No.: HY-W015240S1N-Acetyl-L-glutamic acid-d4 is the deuterium labeled N-Acetyl-L-glutamic acid (HY-W015240). N-Acetyl-L-glutamic acid is a type of glutamic acid that can serve as a component of cell culture media. When combined with media containing inorganic salts, carbohydrates, vitamins, and amino acids, N-Acetyl-L-glutamic acid plays roles in promoting cell growth, enhancing antibody production, etc. N-Acetyl-L-glutamic acid is also an endogenous metabolite that can be found in the brain. Additionally, as an IgE blocker, N-Acetyl-L-glutamic acid can be used in the research of allergic diseases.
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N-Desbutyl bupivacaine-d6
0 ImagesCat. No.: HY-W045132SSynonyms: Desbutylbupivacaine-d6N-Desbutyl bupivacaine-d6 (Desbutylbupivacaine-d6) is the deuterium labeled N-Desbutyl Bupivacaine (HY-W045132). N-Desbutyl Bupivacaine (compound 100) is a metabolite of Bupivacaine (HY-B0405), an NMDA receptor inhibitor and SCN5A antagonist.
